FIP Seminar - Dr. Ricky Wang "The Light Works: Non-invasive 3D optical imaging of tissue morphology and microcirculations in vivo"
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Wed, 09/28/2016 - 12:00 to 13:00
Dr. Ricky Wang
Dr. Ricky Wang, University of Washington "The Light Works: Non-invasive 3D optical imaging of tissue morphology and microcirculations in vivo" - Optical coherence tomography (OCT) is a new medical imaging modality in which the coherent interference of a wide spectrum light source is used to create a high resolution (micron-scale) subsurface image of tissue microstructure. Recently, we have supplemented the microstructural OCT images with additional contrast mechanisms such as blood flow imaging using static and motion contrast, which provide us the ability to perform label-free optical microangiography (OMAG) of microcirculatory tissue beds. The ability to visualize tissue blood flow at the microcirculation level is important in a variety of biomedical applications, some of which (along with the OCT basics and the enabling technologies) will be highlighted in this talk. Examples using OMAG to delineate the dynamic blood perfusion, down to capillary level resolution, within living tissue will be given, including cerebral blood flow in small animals, and retinal blood flow in humans.