Greg D. Field
Adjunct Associate Professor of Neurobiology
My laboratory studies how the retina processes visual scenes and transmits this information to the brain. We use multi-electrode arrays to record the activity of hundreds of retina neurons simultaneously in conjunction with transgenic mouse lines and chemogenetics to manipulate neural circuit function. We are interested in three major areas. First, we work to understand how neurons in the retina are functionally connected. Second we are studying how light-adaptation and circadian rhythms alter visual processing in the retina. Finally, we are working to understand the mechanisms of retinal degenerative conditions and we are investigating potential treatments in animal models.
Appointments and Affiliations
- Adjunct Associate Professor of Neurobiology
- Faculty Network Member of the Duke Institute for Brain Sciences
- Office Location: Bryan Research Building, 311 Research Drive Room 427D, Durham, NC 27710
- Office Phone: (919) 681-7503
- Email Address: email@example.com
- Ph.D. University of Washington, 2004
- NEUROBIO 393: Research Independent Study
- NEUROBIO 793: Research in Neurobiology
- NEUROSCI 493: Research Independent Study 1
- NEUROSCI 494: Research Independent Study 2
- NEUROSCI 495: Research Independent Study 3
In the News
- Living Retina Achieves Sensitivity and Efficiency Engineers Can Only Dream About (Sep 28, 2021)
- Real Neurons are Noisy. Can Neural Implants Figure That Out? (Sep 15, 2020)
- Eyes Have a Natural Version of Night Vision (Sep 13, 2018)
- Duncker, L; Ruda, KM; Field, GD; Pillow, JW, Scalable Variational Inference for Low-Rank Spatiotemporal Receptive Fields., Neural Comput, vol 35 no. 6 (2023), pp. 995-1027 [10.1162/neco_a_01584] [abs].
- Ellis, EM; Paniagua, AE; Scalabrino, ML; Thapa, M; Rathinavelu, J; Jiao, Y; Williams, DS; Field, GD; Fain, GL; Sampath, AP, Cones and cone pathways remain functional in advanced retinal degeneration., Curr Biol, vol 33 no. 8 (2023), pp. 1513-1522.e4 [10.1016/j.cub.2023.03.007] [abs].
- Roy, S; Wang, D; Rudzite, AM; Perry, B; Scalabrino, ML; Thapa, M; Gong, Y; Sher, A; Field, GD, Large-scale interrogation of retinal cell functions by 1-photon light-sheet microscopy., Cell Reports Methods, vol 3 no. 4 (2023) [10.1016/j.crmeth.2023.100453] [abs].
- Scalabrino, ML; Thapa, M; Wang, T; Sampath, AP; Chen, J; Field, GD, Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa. (2023) [10.1101/2023.04.07.536035] [abs].
- Scalabrino, ML; Field, GD, Neuroscience: Visual restoration with optogenetics., Curr Biol, vol 33 no. 3 (2023), pp. R110-R112 [10.1016/j.cub.2022.12.052] [abs].