Lingchong You

You

James L. Meriam Distinguished Professor of Biomedical Engineering

The You lab uses a combination of mathematical modeling, machine learning, and quantitative experiments to elucidate principles underlying the dynamics of microbial communities in time and space and to control these dynamics for applications in computation, engineering, and medicine.

Appointments and Affiliations

  • Professor of Biomedical Engineering
  • James L. Meriam Distinguished Professor of Biomedical Engineering
  • Professor in Molecular Genetics and Microbiology

Contact Information

Education

  • Ph.D. University of Wisconsin - Madison, 2002
  • M.S. University of Science and Technology of China (China), 1997
  • B.S.E. Chengdu University of Science and Technology (China), 1994

Research Interests

Quantitative biology, synthetic biology, machine learning, antibiotic resistance, microbiome

Awards, Honors, and Distinctions

  • Fellow. American Institute for Medical and Biological Engineering. 2019
  • Faculty Early Career Development (CAREER) Program. National Science Foundation. 2010
  • Young Professor Award. DuPont. 2008
  • Fellowships for Science and Engineering. David and Lucile Packard Foundation. 2006

Courses Taught

  • BIOLOGY 293-1: Research Independent Study
  • BME 394: Projects in Biomedical Engineering (GE)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 574: Modeling and Engineering Gene Circuits (GE, MC)
  • BME 713S: QBio Seminar Series
  • BME 791: Graduate Independent Study
  • BME 792: Continuation of Graduate Independent Study
  • CBB 574: Modeling and Engineering Gene Circuits (GE, MC)
  • EGR 393: Research Projects in Engineering
  • MGM 293: Research Independent Study I
  • MGM 593: Research Independent Study
  • PHARM 394: Research Independent Study

In the News

Representative Publications

  • Kim, K; Wang, T; Ma, HR; Şimşek, E; Li, B; Andreani, V; You, L, Mapping single-cell responses to population-level dynamics during antibiotic treatment, Molecular Systems Biology, vol 19 no. 7 (2023) [10.15252/msb.202211475] [abs].
  • Şimşek, E; Yao, Y; Lee, D; You, L, Toward predictive engineering of gene circuits., Trends in Biotechnology, vol 41 no. 6 (2023), pp. 760-768 [10.1016/j.tibtech.2022.11.001] [abs].
  • Dai, Y; Chamberlayne, CF; Messina, MS; Chang, CJ; Zare, RN; You, L; Chilkoti, A, Interface of biomolecular condensates modulates redox reactions., Chem, vol 9 no. 6 (2023), pp. 1594-1609 [10.1016/j.chempr.2023.04.001] [abs].
  • Silver, A; You, L, A change of phase., Nature Chemical Biology, vol 19 no. 4 (2023), pp. 397-398 [10.1038/s41589-022-01209-x] [abs].
  • Dai, Y; Farag, M; Lee, D; Zeng, X; Kim, K; Son, H-I; Guo, X; Su, J; Peterson, N; Mohammed, J; Ney, M; Shapiro, DM; Pappu, RV; Chilkoti, A; You, L, Programmable synthetic biomolecular condensates for cellular control., Nature Chemical Biology, vol 19 no. 4 (2023), pp. 518-528 [10.1038/s41589-022-01252-8] [abs].