FIP IN-PERSON Seminar "Mesoscopic and microscopic imaging of the brain: from intra-operative guidance in patients to neural activity assessment in freely-moving rodents"
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Wed, 11/03/2021 - 12:00 to 13:00
Dr. Xingde Li, Professor, Department of Biomedical Engineering, Johns Hopkins University
HYBRID event: You may participate in person at Schiciano Auditorium Side B or by Zoom link.
This presentation will focus on our recent development of biophotonics imaging technologies for intra-operative detection of brain cancer infiltration in patients, and on functional brain imaging in freely-moving rodents. The technology platforms include quantitative OCT and scanning two-photon fiberscopy. The working principles, algorithms, and key engineering solutions of the technologies will be briefly discussed, followed by the results of intra-operative studies in patients and preliminary functional brain imaging studies in freely-behaving animals. Other closely related and recently developed endoscopy technologies and their applications will also be presented. The last part of this presentation will discuss our initial attempt of using deep learning for automated image segmentation, quantitative analysis, image compression, and imaging speed/quality augmentation.
Xingde Li, Professor of Biomedical Engineering Johns Hopkins and Fellow of OSA, SPIE, and AIMBE, received his PhD degree in Physics from the University of Pennsylvania in 1998. His research centers on biophotonics imaging technologies and their translational and basic research applications. He has published about 130 peer-reviewed journal papers, with a total citation ~19,800 and an H-index~60 (Google Scholar). He has served on many committees of various societies (including the chair of Emerging Technologies Committee of IEEE-EMBS), and has chaired many international conferences. He is serving (or served) as a topical editor or associate editor for Optics Letters, Biomedical Optics Express, Journal of Biomedical Optics, IEEE Transactions on Biomedical Engineering, (Nature) Light: Science and Applications etc. He is also the lead founding Editor-in-Chief for the recently launched AAAS Science Partner Journal - BME Frontiers.