David N. Beratan
R.J. Reynolds Professor of Chemistry
Dr. Beratan is developing theoretical approaches to understand the function of complex molecular and macromolecular systems, including: the molecular underpinnings of energy harvesting and charge transport in biology; the mechanism of solar energy capture and conversion in man-made structures; the nature of charge conductivity in naturally occurring nucleic acids and in synthetic constructs, including the photochemical repair of damaged DNA in extremophiles; CH bond activation by copper oxygenase enzymes; the flow of charge in bacterial appendages on the micrometer length scale; the theoretical foundations for inverse molecular design - the property driven discovery of chemical structures with optimal properties; the exploitation of molecular diversity in the mapping of molecular and materials "space"; the use of infra-red excitation to manipulate electron transport through molecules; the optical signatures of molecular chirality and the influence of chirality on charge transport. Prof. Beratan is affiliated with the Departments of Chemistry, Biochemistry, Physics, as well as Duke's programs in Computational Biology and Bioinformatics, Structural Biology and Biophysics, Nanosciences, and Phononics.
Appointments and Affiliations
- R.J. Reynolds Professor of Chemistry
- Professor of Chemistry
- Professor of Biochemistry
- Professor of Physics
- Faculty Network Member of The Energy Initiative
- Office Location: 5311 French Science Center, Durham, NC 27708
- Office Phone: (919) 660-1526
- Email Address: firstname.lastname@example.org
- Ph.D. California Institute of Technology, 1986
- B.S. Duke University, 1980
Awards, Honors, and Distinctions
- Florida Award. American Chemical Society. 2017
- Charles H. Herty Medal . American Chemical Society Georgia Section. 2015
- Elected Fellow. American Chemical Society. 2013
- Feynman Prize for Nanoscience (Theory). Foresight Institute. 2013
- Elected Fellow. American Association for the Advancement of Science. 2002
- Conrad E. Ronneberg Visiting Scholar. University of Chicago. 2001
- Elected Fellow. American Physical Society. 2001
- Ralph & Lucy Hirschmann Visiting Professorship. University of Pennsylvania. 2000
- Fellow. J.S. Guggenheim Foundation. 1999
- Visiting Fellow. All Souls College, University of Oxford. 1999
- National Young Investigator Award . National Science Foundation. 1992
- ARTS&SCI 302: How Does Biology Work? The Physical and Chemical Underpinnings of Biological Nanomachines
- CHEM 302: How Does Biology Work? The Physical and Chemical Underpinnings of Biological Nanomachines
- CHEM 590: Special Topics in Chemistry
In the News
- How Earths Earliest Lifeforms Protected Their Genes (Mar 2, 2018 | Duke Research Blog)
- Tailored DNA Shifts Electrons Into The 'Fast Lane' (Jun 20, 2016)
- David Beratan and the Inner Workings of the Machines of Biology (May 6, 2015)
- Beratan, Quin named ACS Fellows (Aug 8, 2013)
- Teo, RD; Rousseau, BJG; Smithwick, ER; Di Felice, R; Beratan, DN; Migliore, A, Charge Transfer between [4Fe4S] Proteins and DNA Is Unidirectional: Implications for Biomolecular Signaling., Chem, vol 5 no. 1 (2019), pp. 122-137 [10.1016/j.chempr.2018.09.026] [abs].
- Seefeldt, LC; Peters, JW; Beratan, DN; Bothner, B; Minteer, SD; Raugei, S; Hoffman, BM, Control of electron transfer in nitrogenase., Current Opinion in Chemical Biology, vol 47 (2018), pp. 54-59 [10.1016/j.cbpa.2018.08.011] [abs].
- Skourtis, SS; Beratan, DN, Editorial overview: Biological pathways for electrons, protons and photo-excitations., Current Opinion in Chemical Biology, vol 47 (2018), pp. A1-A3 [10.1016/j.cbpa.2018.09.023] [abs].
- Teo, RD; Smithwick, ER; Migliore, A; Beratan, DN, A single AT-GC exchange can modulate charge transfer-induced p53-DNA dissociation., Chemical Communications, vol 55 no. 2 (2018), pp. 206-209 [10.1039/c8cc09048c] [abs].
- Teo, RD; Terai, K; Migliore, A; Beratan, DN, Electron transfer characteristics of 2'-deoxy-2'-fluoro-arabinonucleic acid, a nucleic acid with enhanced chemical stability., Physical Chemistry Chemical Physics : Pccp, vol 20 no. 41 (2018), pp. 26063-26067 [10.1039/c8cp04816a] [abs].