Huanghe Yang


Assistant Professor of Biochemistry

Appointments and Affiliations

  • Assistant Professor of Biochemistry
  • Assistant Professor in Neurobiology
  • Faculty Network Member of the Duke Institute for Brain Sciences

Contact Information

  • Office Location: 213 Nanaline H Duke, Box 3711, DUMC, Durham, NC 27710
  • Office Phone: (919) 684-1406
  • Email Address:
  • Websites:


  • Ph.D. Washington University in St. Louis, 2008

Awards, Honors, and Distinctions

  • NIH Director's New Innovator Award. NIH. 2017
  • Pathway to Independence Award (K99/R00). NINDS. 2014

Courses Taught

  • BIOCHEM 393: Research Independent Study
  • BIOCHEM 593: Research Independent Study
  • NEUROBIO 793: Research in Neurobiology

In the News

Representative Publications

  • Le, T; Le, SC; Zhang, Y; Liang, P; Yang, H, Evidence that polyphenols do not inhibit the phospholipid scramblase TMEM16F., The Journal of Biological Chemistry, vol 295 no. 35 (2020), pp. 12537-12544 [10.1074/jbc.AC120.014872] [abs].
  • Liao, C; Zhang, Y; Fan, C; Herring, LE; Liu, J; Locasale, JW; Takada, M; Zhou, J; Zurlo, G; Hu, L; Simon, JM; Ptacek, TS; Andrianov, VG; Loza, E; Peng, Y; Yang, H; Perou, CM; Zhang, Q, Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer., Cancer Discov (2020) [10.1158/2159-8290.CD-20-0288] [abs].
  • Zhang, G; Gibson, RA; McDonald, M; Liang, P; Kang, PW; Shi, J; Yang, H; Cui, J; Mikati, MA, A Gain-of-Function Mutation in KCNMA1 Causes Dystonia Spells Controlled With Stimulant Therapy., Mov Disord (2020) [10.1002/mds.28138] [abs].
  • Zhang, Y; Le, T; Grabau, R; Mohseni, Z; Kim, H; Natale, DR; Feng, L; Pan, H; Yang, H, TMEM16F phospholipid scramblase mediates trophoblast fusion and placental development., Science Advances, vol 6 no. 19 (2020) [10.1126/sciadv.aba0310] [abs].
  • Le, SC; Jia, Z; Chen, J; Yang, H, Molecular basis of PIP2-dependent regulation of the Ca2+-activated chloride channel TMEM16A., Nature Communications, vol 10 no. 1 (2019) [10.1038/s41467-019-11784-8] [abs].