Junjie Yao

Yao

Associate Professor of Biomedical Engineering

Our mission at PI-Lab is to develop state-of-the-art photoacoustic tomography (PAT) technologies and translate PAT advances into diagnostic and therapeutic applications, especially in functional brain imaging and early cancer theranostics. PAT is the most sensitive modality for imaging rich optical absorption contrast over a wide range of spatial scales at high speed, and is one of the fastest growing biomedical imaging technologies. Using numerous endogenous and exogenous contrasts, PAT can provide high-resolution images at scales covering organelles, cells, tissues, organs, small-animal organisms, up to humans, and can reveal tissue’s anatomical, functional, metabolic, and even histologic properties, with molecular and neuronal specificity.

At PI-Lab, we develop PAT technologies with novel and advanced imaging performance, in terms of spatial resolutions, imaging speed, penetration depth, detection sensitivity, and functionality. We are interested with all aspects of PAT technology innovations, including efficient light illumination, high-sensitivity ultrasonic detection, super-resolution PAT, high-speed imaging acquisition, novel PA genetic contrast, and precise image reconstruction. On top of the technological advancements, we are devoted to serve the broad life science and medical communities with matching PAT systems for various research and clinical needs. With its unique contrast mechanism, high scalability, and inherent functional and molecular imaging capabilities, PAT is well suited for a variety of pre-clinical applications, especially for studying tumor angiogenesis, cancer hypoxia, and brain disorders; it is also a promising tool for clinical applications in procedures such as cancer screening, melanoma staging, and endoscopic examination.

Appointments and Affiliations

  • Associate Professor of Biomedical Engineering
  • Associate Professor in Neurology
  • Affiliate, Duke Global Health Institute
  • Faculty Network Member of the Duke Institute for Brain Sciences
  • Member of the Duke Cancer Institute

Contact Information

Education

  • Ph.D. Washington University in St. Louis, 2012

Research Interests

Photoacoustic tomography (PAT) technologies, and translating PAT advances into diagnostic and therapeutic applications, especially in functional brain imaging and early cancer theranostics.

Awards, Honors, and Distinctions

  • Fellow. Optica (formally OSA). 2022
  • Early Career Development (CAREER) Award. National Science Foundation (NSF). 2022
  • 2019 Young Investigator Award. IEEE Photonics Society . 2019
  • Collaborative Sciences Award. American Heart Association . 2018
  • OSA/Quantel Bright Idea Competition (Finalist). Optical Society of America. 2017
  • Seno Medical Best Paper Award. SPIE conference Photons Plus Ultrasound 2016: Imaging and Sensing. 2016
  • Seno Medical Best Paper Award. SPIE conference Photons Plus Ultrasound 2015: Imaging and Sensing . 2015
  • Seno Medical Best Paper Award. SPIE conference Photons Plus Ultrasound 2013: Imaging and Sensing . 2013
  • Chinese Government Award for Outstanding Self-financed Students Aboard. The Education Ministry of China. 2012
  • Best Master Dissertation Award. Tsinghua University. 2008
  • Comprehensive Student Fellowship. Tsinghua University. 2008
  • KangShien Outstanding Graduate Fellowship. Tsinghua University. 2006
  • CyrusTang Fellowship (2002-2006). Tsinghua University. 2002

Courses Taught

  • BME 792: Continuation of Graduate Independent Study
  • BME 791: Graduate Independent Study
  • BME 790L: Advanced Topics with the Lab for Graduate Students in Biomedical Engineering
  • BME 590: Special Topics in Biomedical Engineering
  • BME 553: Deep Tissue Optics (GE, IM)
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 394: Projects in Biomedical Engineering (GE)
  • BME 303L: Modern Diagnostic Imaging Systems (AC or GE)

In the News

Representative Publications

  • Maharjan, S; Ma, C; Singh, B; Kang, H; Orive, G; Yao, J; Shrike Zhang, Y, Advanced 3D imaging and organoid bioprinting for biomedical research and therapeutic applications., Advanced drug delivery reviews, vol 208 (2024) [10.1016/j.addr.2024.115237] [abs].
  • Zhu, X; Huang, Q; Jiang, L; Nguyen, V-T; Vu, T; Devlin, G; Shaima, J; Wang, X; Chen, Y; Ma, L; Xiang, K; Wang, E; Rong, Q; Zhou, Q; Kang, Y; Asokan, A; Feng, L; Hsu, S-WD; Shen, X; Yao, J, Longitudinal intravital imaging of mouse placenta., Sci Adv, vol 10 no. 12 (2024) [10.1126/sciadv.adk1278] [abs].
  • Zhang, W; Li, Y; Fung, AA; Li, Z; Jang, H; Zha, H; Chen, X; Gao, F; Wu, JY; Sheng, H; Yao, J; Skowronska-Krawczyk, D; Jain, S; Shi, L, Multi-molecular hyperspectral PRM-SRS microscopy., Nat Commun, vol 15 no. 1 (2024) [10.1038/s41467-024-45576-6] [abs].
  • Vu, T; Klippel, P; Canning, AJ; Ma, C; Zhang, H; Kasatkina, LA; Tang, Y; Xia, J; Verkhusha, VV; Vo-Dinh, T; Jing, Y; Yao, J, On the Importance of Low-Frequency Signals in Functional and Molecular Photoacoustic Computed Tomography., IEEE Trans Med Imaging, vol 43 no. 2 (2024), pp. 771-783 [10.1109/TMI.2023.3320668] [abs].
  • Vu, T; Klippel, P; Canning, AJ; Ma, C; Zhang, H; Kasatkina, LA; Tang, Y; Xia, J; Verkhusha, VV; Vo-Dinh, T; Jing, Y; Yao, J, On the Importance of Low-Frequency Signals in Functional and Molecular Photoacoustic Computed Tomography., IEEE transactions on medical imaging, vol 43 no. 2 (2024), pp. 771-783 [10.1109/tmi.2023.3320668] [abs].
  • Cho, S-W; Nguyen, VT; DiSpirito, A; Yang, J; Kim, C-S; Yao, J, Sounding out the dynamics: a concise review of high-speed photoacoustic microscopy., Journal of biomedical optics, vol 29 no. Suppl 1 (2024) [10.1117/1.jbo.29.s1.s11521] [abs].
  • Kuang, X; Rong, Q; Belal, S; Vu, T; López López, AM; Wang, N; Arıcan, MO; Garciamendez-Mijares, CE; Chen, M; Yao, J; Zhang, YS, Self-enhancing sono-inks enable deep-penetration acoustic volumetric printing., Science (New York, N.Y.), vol 382 no. 6675 (2023), pp. 1148-1155 [10.1126/science.adi1563] [abs].
  • Lee, Y; Rong, Q; Song, K-H; Czaplewski, DA; Zhang, HF; Yao, J; Sun, C, Theoretical and experimental study on the detection limit of the micro-ring resonator based ultrasound point detectors., Photoacoustics, vol 34 (2023) [10.1016/j.pacs.2023.100574] [abs].
  • Xiang, G; Chen, J; Ho, D; Sankin, G; Zhao, X; Liu, Y; Wang, K; Dolbow, J; Yao, J; Zhong, P, Shock waves generated by toroidal bubble collapse are imperative for kidney stone dusting during Holmium:YAG laser lithotripsy., Ultrasonics sonochemistry, vol 101 (2023) [10.1016/j.ultsonch.2023.106649] [abs].
  • Park, H; Yao, J; Jing, Y, A frequency-domain model-based reconstruction method for transcranial photoacoustic imaging: A 2D numerical investigation., Photoacoustics, vol 33 (2023) [10.1016/j.pacs.2023.100561] [abs].
  • Rong, Q; Taboada, C; Águila, ÁD; Merutka, I; Jayasundara, N; Zeng, Y; Yang, W; Zhou, Q; Yao, J, From Ultraviolet to Near-Infrared: Label-Free Reflection-Mode Hyperspectral Photoacoustic Microscopy for Single-Cell Biochemical Mapping, GEN Biotechnology, vol 2 no. 5 (2023), pp. 435-444 [10.1089/genbio.2023.0035] [abs].
  • Yao, J; Kim, C; Kolios, M; Hu, S, Editorial: Breaking the speed limits in photoacoustic microscopy., Photoacoustics, vol 32 (2023) [10.1016/j.pacs.2023.100541] [abs].
  • Ma, C; Kuang, X; Chen, M; Menozzi, L; Jiang, L; Zhou, Q; Zhang, YS; Yao, J, Multiscale photoacoustic tomography using reversibly switchable thermochromics., Journal of biomedical optics, vol 28 no. 8 (2023) [10.1117/1.jbo.28.8.082804] [abs].
  • Wu, H; Tang, Y; Zhang, B; Klippel, P; Jing, Y; Yao, J; Jiang, X, Miniaturized Stacked Transducer for Intravascular Sonothrombolysis With Internal-Illumination Photoacoustic Imaging Guidance and Clot Characterization., IEEE transactions on bio-medical engineering, vol 70 no. 8 (2023), pp. 2279-2288 [10.1109/tbme.2023.3240725] [abs].
  • Kim, H; Zhang, B; Wu, H; Yao, J; Shi, C; Jiang, X, Vortex-ultrasound for microbubble-mediated thrombolysis of retracted clots., Applied physics letters, vol 123 no. 7 (2023) [10.1063/5.0155223] [abs].
  • Zhang, D; Wang, W; Zhu, X; Li, R; Liu, W; Chen, M; Vu, T; Jiang, L; Zhou, Q; Evans, CL; Turner, DA; Sheng, H; Levy, JH; Luo, J; Yang, W; Yao, J; Hoffmann, U, Epinephrine-induced Effects on Cerebral Microcirculation and Oxygenation Dynamics Using Multimodal Monitoring and Functional Photoacoustic Microscopy., Anesthesiology, vol 139 no. 2 (2023), pp. 173-185 [10.1097/ALN.0000000000004592] [abs].
  • Tang, Y; Dong, Z; Wang, N; Del Aguila, A; Johnston, N; Vu, T; Ma, C; Xu, Y; Yang, W; Song, P; Yao, J, Non-invasive Deep-Brain Imaging with 3D Integrated Photoacoustic Tomography and Ultrasound Localization Microscopy (3D-PAULM)., ArXiv (2023) [abs].
  • Menozzi, L; Del Águila, Á; Vu, T; Ma, C; Yang, W; Yao, J, Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke., J Vis Exp no. 196 (2023) [10.3791/65319] [abs].
  • Veverka, M; Menozzi, L; Yao, J, The sound of blood: photoacoustic imaging in blood analysis., Medicine in novel technology and devices, vol 18 (2023) [10.1016/j.medntd.2023.100219] [abs].
  • Li, R; Duan, W; Zhang, D; Hoffmann, U; Yao, J; Yang, W; Sheng, H, Mouse Cardiac Arrest Model for Brain Imaging and Brain Physiology Monitoring During Ischemia and Resuscitation., J Vis Exp no. 194 (2023) [10.3791/65340] [abs].
  • Wang, R; Zhu, J; Xia, J; Yao, J; Shi, J; Li, C, Photoacoustic imaging with limited sampling: a review of machine learning approaches., Biomedical optics express, vol 14 no. 4 (2023), pp. 1777-1799 [10.1364/boe.483081] [abs].
  • Wang, Z; Li, Q; Kolls, BJ; Mace, B; Yu, S; Li, X; Liu, W; Chaparro, E; Shen, Y; Dang, L; Del Águila, Á; Bernstock, JD; Johnson, KR; Yao, J; Wetsel, WC; Moore, SD; Turner, DA; Yang, W, Sustained overexpression of spliced X-box-binding protein-1 in neurons leads to spontaneous seizures and sudden death in mice., Commun Biol, vol 6 no. 1 (2023) [10.1038/s42003-023-04594-8] [abs].
  • Oliinyk, OS; Ma, C; Pletnev, S; Baloban, M; Taboada, C; Sheng, H; Yao, J; Verkhusha, VV, Author Correction: Deep-tissue SWIR imaging using rationally designed small red-shifted near-infrared fluorescent protein., Nat Methods, vol 20 no. 3 (2023) [10.1038/s41592-023-01798-y] [abs].
  • Jing, Y; Li, M; Gu, J; Zhong, P; Yao, J, Time-resolved passive cavitation mapping using the transient angular spectrum approach, The Journal of the Acoustical Society of America, vol 153 no. 3_supplement (2023), pp. A268-A268 [10.1121/10.0018806] [abs].
  • Yao, J; Nguyen, VT, High-Speed Photoacoustic Microscopy Captures Processes Within Tissue, Biophotonics International, vol 30 no. 2 (2023), pp. 29-34 [abs].
  • Cupil-Garcia, V; Li, JQ; Norton, SJ; Odion, RA; Strobbia, P; Menozzi, L; Ma, C; Hu, J; Zentella, R; Boyanov, MI; Finfrock, YZ; Gursoy, D; Douglas, DS; Yao, J; Sun, T-P; Kemner, KM; Vo-Dinh, T, Plasmonic nanorod probes' journey inside plant cells for in vivo SERS sensing and multimodal imaging., Nanoscale, vol 15 no. 13 (2023), pp. 6396-6407 [10.1039/d2nr06235f] [abs].
  • Xiang, G; Li, D; Chen, J; Mishra, A; Sankin, G; Zhao, X; Tang, Y; Wang, K; Yao, J; Zhong, P, Dissimilar cavitation dynamics and damage patterns produced by parallel fiber alignment to the stone surface in holmium:yttrium aluminum garnet laser lithotripsy., Physics of fluids (Woodbury, N.Y. : 1994), vol 35 no. 3 (2023) [10.1063/5.0139741] [abs].
  • Tang, Y; Tang, S; Huang, C; Klippel, P; Ma, C; Caso, N; Chen, S; Jing, Y; Yao, J, High-fidelity deep functional photoacoustic tomography enhanced by virtual point sources., Photoacoustics, vol 29 (2023) [10.1016/j.pacs.2023.100450] [abs].
  • Menozzi, L; Del Águila, Á; Vu, T; Ma, C; Yang, W; Yao, J, Three-dimensional non-invasive brain imaging of ischemic stroke by integrated photoacoustic, ultrasound and angiographic tomography (PAUSAT)., Photoacoustics, vol 29 (2023) [10.1016/j.pacs.2022.100444] [abs].
  • Li, M; Beaumont, N; Ma, C; Rojas, J; Vu, T; Harlacher, M; O'Connell, G; Gessner, RC; Kilian, H; Kasatkina, L; Chen, Y; Huang, Q; Shen, X; Lovell, JF; Verkhusha, VV; Czernuszewicz, T; Yao, J, Three-Dimensional Deep-Tissue Functional and Molecular Imaging by Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT)., IEEE Trans Med Imaging, vol 41 no. 10 (2022), pp. 2704-2714 [10.1109/TMI.2022.3168859] [abs].
  • Chen, J; Li, D; Yu, W; Ma, Z; Li, C; Xiang, G; Wu, Y; Yao, J; Zhong, P, The Effects of Scanning Speed and Standoff Distance of the Fiber on Dusting Efficiency during Short Pulse Holmium: YAG Laser Lithotripsy., J Clin Med, vol 11 no. 17 (2022) [10.3390/jcm11175048] [abs].
  • Kasatkina, LA; Ma, C; Matlashov, ME; Vu, T; Li, M; Kaberniuk, AA; Yao, J; Verkhusha, VV, Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model., Nature communications, vol 13 no. 1 (2022) [10.1038/s41467-022-30547-6] [abs].
  • Tang, Y; Wu, H; Klippel, P; Zhang, B; Huang, H-YS; Jing, Y; Jiang, X; Yao, J, Deep thrombosis characterization using photoacoustic imaging with intravascular light delivery., Biomedical engineering letters, vol 12 no. 2 (2022), pp. 135-145 [10.1007/s13534-022-00216-0] [abs].
  • Zhang, H; Bo, W; Wang, D; DiSpirito, A; Huang, C; Nyayapathi, N; Zheng, E; Vu, T; Gong, Y; Yao, J; Xu, W; Xia, J, Deep-E: A Fully-Dense Neural Network for Improving the Elevation Resolution in Linear-Array-Based Photoacoustic Tomography., IEEE transactions on medical imaging, vol 41 no. 5 (2022), pp. 1279-1288 [10.1109/tmi.2021.3137060] [abs].
  • Duan, T; Peng, X; Chen, M; Zhang, D; Gao, F; Yao, J, Detection of weak optical absorption by optical-resolution photoacoustic microscopy., Photoacoustics, vol 25 (2022) [10.1016/j.pacs.2022.100335] [abs].
  • Dong, B; Yao, J; Deán-Ben, XL, Editorial: Advances in Photoacoustic Neuroimaging., Frontiers in neuroscience, vol 16 (2022) [10.3389/fnins.2022.859515] [abs].
  • Zhang, D; Li, R; Chen, M; Vu, T; Sheng, H; Yang, W; Hoffmann, U; Luo, J; Yao, J, Photoacoustic imaging of in vivo hemodynamic responses to sodium nitroprusside., J Biophotonics, vol 14 no. 7 (2021) [10.1002/jbio.202000478] [abs].
  • Li, M; Gu, J; Vu, T; Sankin, G; Zhong, P; Yao, J; Jing, Y, Time-Resolved Passive Cavitation Mapping Using the Transient Angular Spectrum Approach., IEEE transactions on ultrasonics, ferroelectrics, and frequency control, vol 68 no. 7 (2021), pp. 2361-2369 [10.1109/tuffc.2021.3062357] [abs].
  • Tang, Y; Yao, J, 3D Monte Carlo simulation of light distribution in mouse brain in quantitative photoacoustic computed tomography., Quantitative imaging in medicine and surgery, vol 11 no. 3 (2021), pp. 1046-1059 [10.21037/qims-20-815] [abs].
  • Li, M; Sankin, G; Vu, T; Yao, J; Zhong, P, Tri-modality cavitation mapping in shock wave lithotripsy., The Journal of the Acoustical Society of America, vol 149 no. 2 (2021) [10.1121/10.0003555] [abs].
  • DiSpirito, A; Li, D; Vu, T; Chen, M; Zhang, D; Luo, J; Horstmeyer, R; Yao, J, Reconstructing Undersampled Photoacoustic Microscopy Images Using Deep Learning., IEEE transactions on medical imaging, vol 40 no. 2 (2021), pp. 562-570 [10.1109/tmi.2020.3031541] [abs].
  • Li, M; Vu, T; Sankin, G; Winship, B; Boydston, K; Terry, R; Zhong, P; Yao, J, Internal-Illumination Photoacoustic Tomography Enhanced by a Graded-Scattering Fiber Diffuser., IEEE transactions on medical imaging, vol 40 no. 1 (2021), pp. 346-356 [10.1109/tmi.2020.3027199] [abs].
  • III, AD; Li, D; Vu, T; Chen, M; Zhang, D; Luo, J; Horstmeyer, R; Yao, J, Reconstructing Undersampled Photoacoustic Microscopy Images Using Deep Learning., IEEE Trans. Medical Imaging, vol 40 (2021), pp. 562-570 [10.1109/TMI.2020.3031541] [abs].
  • Wu, H; Tang, Y; Kim, H; Yao, J; Jiang, X, Fiber based laser ultrasound transducer for intravascular thrombolysis with detective photoacoustic imaging, IEEE International Ultrasonics Symposium, IUS, vol 2020-September (2020) [10.1109/IUS46767.2020.9251732] [abs].
  • Li, M; Yao, J, Internal-Illumination Photoacoustic Tomography Enhanced by a Graded-scattering Fiber Diffuser, 2020 IEEE Photonics Conference, IPC 2020 - Proceedings (2020) [10.1109/IPC47351.2020.9252241] [abs].
  • Yao, J, Ultrasfast Wide-field Photoacoustic Microscopy of Small-animal Models, 2020 IEEE Photonics Conference, IPC 2020 - Proceedings (2020) [10.1109/IPC47351.2020.9252208] [abs].
  • Vu, T; Li, M; Humayun, H; Zhou, Y; Yao, J, A generative adversarial network for artifact removal in photoacoustic computed tomography with a linear-array transducer., Experimental biology and medicine (Maywood, N.J.), vol 245 no. 7 (2020), pp. 597-605 [10.1177/1535370220914285] [abs].
  • Li, Y; Li, L; Zhu, L; Maslov, K; Shi, J; Hu, P; Bo, E; Yao, J; Liang, J; Wang, L; Wang, LV, Snapshot Photoacoustic Topography Through an Ergodic Relay for High-throughput Imaging of Optical Absorption., Nature photonics, vol 14 no. 3 (2020), pp. 164-170 [10.1038/s41566-019-0576-2] [abs].
  • Li, M; Lan, B; Sankin, G; Zhou, Y; Liu, W; Xia, J; Wang, D; Trahey, G; Zhong, P; Yao, J, Simultaneous Photoacoustic Imaging and Cavitation Mapping in Shockwave Lithotripsy., IEEE transactions on medical imaging, vol 39 no. 2 (2020), pp. 468-477 [10.1109/tmi.2019.2928740] [abs].
  • Onufer, EJ; Aladegbami, B; Imai, T; Seiler, K; Bajinting, A; Courtney, C; Sutton, S; Bustos, A; Yao, J; Yeh, C-H; Sescleifer, A; Wang, LV; Guo, J; Warner, BW, EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis., PloS one, vol 15 no. 9 (2020) [10.1371/journal.pone.0236964] [abs].
  • Tang, Y; Qian, X; Lee, DJ; Zhou, Q; Yao, J, From Light to Sound: Photoacoustic and Ultrasound Imaging in Fundamental Research of Alzheimer's Disease., OBM neurobiology, vol 4 no. 2 (2020) [10.21926/obm.neurobiol.2002056] [abs].
  • Vu, T; Razansky, D; Yao, J, Listening to tissues with new light: recent technological advances in photoacoustic imaging., Journal of optics (2010), vol 21 no. 10 (2019) [10.1088/2040-8986/ab3b1a] [abs].
  • Chen, M; Knox, HJ; Tang, Y; Liu, W; Nie, L; Chan, J; Yao, J, Simultaneous photoacoustic imaging of intravascular and tissue oxygenation., Optics letters, vol 44 no. 15 (2019), pp. 3773-3776 [10.1364/ol.44.003773] [abs].
  • Liang, B; Liu, W; Zhan, Q; Li, M; Zhuang, M; Liu, QH; Yao, J, Impacts of the murine skull on high-frequency transcranial photoacoustic brain imaging., Journal of biophotonics, vol 12 no. 7 (2019) [10.1002/jbio.201800466] [abs].
  • Humayun, H; Yao, J, Imaging the aged brain: pertinence and methods., Quantitative imaging in medicine and surgery, vol 9 no. 5 (2019), pp. 842-857 [10.21037/qims.2019.05.06] [abs].
  • Zhou, Y; Li, M; Liu, W; Sankin, G; Luo, J; Zhong, P; Yao, J, Thermal Memory Based Photoacoustic Imaging of Temperature., Optica, vol 6 no. 2 (2019), pp. 198-205 [10.1364/optica.6.000198] [abs].
  • Lan, B; Liu, W; Wang, Y-C; Shi, J; Li, Y; Xu, S; Sheng, H; Zhou, Q; Zou, J; Hoffmann, U; Yang, W; Yao, J, High-speed widefield photoacoustic microscopy of small-animal hemodynamics., Biomed Opt Express, vol 9 no. 10 (2018), pp. 4689-4701 [10.1364/BOE.9.004689] [abs].
  • Vienneau, E; Liu, W; Yao, J, Dual-view acoustic-resolution photoacoustic microscopy with enhanced resolution isotropy., Optics letters, vol 43 no. 18 (2018), pp. 4413-4416 [10.1364/ol.43.004413] [abs].
  • Shi, J; Tang, Y; Yao, J, Advances in super-resolution photoacoustic imaging., Quantitative imaging in medicine and surgery, vol 8 no. 8 (2018), pp. 724-732 [10.21037/qims.2018.09.14] [abs].
  • Liu, W; Shcherbakova, DM; Kurupassery, N; Li, Y; Zhou, Q; Verkhusha, VV; Yao, J, Quad-mode functional and molecular photoacoustic microscopy., Scientific reports, vol 8 no. 1 (2018) [10.1038/s41598-018-29249-1] [abs].
  • Li, L; Shemetov, AA; Baloban, M; Hu, P; Zhu, L; Shcherbakova, DM; Zhang, R; Shi, J; Yao, J; Wang, LV; Verkhusha, VV, Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo., Nature communications, vol 9 no. 1 (2018) [10.1038/s41467-018-05231-3] [abs].
  • Liu, W; Zhou, Y; Wang, M; Li, L; Vienneau, E; Chen, R; Luo, J; Xu, C; Zhou, Q; Wang, LV; Yao, J, Correcting the limited view in optical-resolution photoacoustic microscopy., Journal of biophotonics, vol 11 no. 2 (2018) [10.1002/jbio.201700196] [abs].
  • Liu, W; Lan, B; Hu, L; Chen, R; Zhou, Q; Yao, J, Photoacoustic thermal flowmetry with a single light source., Journal of biomedical optics, vol 22 no. 9 (2017), pp. 1-6 [10.1117/1.jbo.22.9.096001] [abs].
  • Brunker, J; Yao, J; Laufer, J; Bohndiek, SE, Photoacoustic imaging using genetically encoded reporters: a review., Journal of biomedical optics, vol 22 no. 7 (2017) [10.1117/1.jbo.22.7.070901] [abs].
  • Yao, J, When pressure meets light: detecting the photoacoustic effect at the origin., Light, science & applications, vol 6 no. 6 (2017) [10.1038/lsa.2017.62] [abs].
  • Li, L; Zhu, L; Ma, C; Lin, L; Yao, J; Wang, L; Maslov, K; Zhang, R; Chen, W; Shi, J; Wang, LV, Single-impulse Panoramic Photoacoustic Computed Tomography of Small-animal Whole-body Dynamics at High Spatiotemporal Resolution., Nature biomedical engineering, vol 1 no. 5 (2017) [10.1038/s41551-017-0071] [abs].
  • Wang, LV; Yao, J, A practical guide to photoacoustic tomography in the life sciences., Nature methods, vol 13 no. 8 (2016), pp. 627-638 [10.1038/nmeth.3925] [abs].
  • Zhou, Y; Yao, J; Wang, LV, Tutorial on photoacoustic tomography., Journal of biomedical optics, vol 21 no. 6 (2016) [10.1117/1.jbo.21.6.061007] [abs].
  • Lin, L; Yao, J; Li, L; Wang, LV, In vivo photoacoustic tomography of myoglobin oxygen saturation., Journal of biomedical optics, vol 21 no. 6 (2016) [10.1117/1.jbo.21.6.061002] [abs].
  • Hai, P; Yao, J; Li, G; Li, C; Wang, LV, Photoacoustic elastography., Optics letters, vol 41 no. 4 (2016), pp. 725-728 [10.1364/ol.41.000725] [abs].
  • Yao, J; Kaberniuk, AA; Li, L; Shcherbakova, DM; Zhang, R; Wang, L; Li, G; Verkhusha, VV; Wang, LV, Multiscale photoacoustic tomography using reversibly switchable bacterial phytochrome as a near-infrared photochromic probe., Nature methods, vol 13 no. 1 (2016), pp. 67-73 [10.1038/nmeth.3656] [abs].
  • Yao, J; Song, L; Wang, LV, Photoacoustic microscopy: superdepth, superresolution, and superb contrast., IEEE pulse, vol 6 no. 3 (2015), pp. 34-37 [10.1109/mpul.2015.2409100] [abs].
  • Yao, J; Wang, L; Yang, J-M; Maslov, KI; Wong, TTW; Li, L; Huang, C-H; Zou, J; Wang, LV, High-speed label-free functional photoacoustic microscopy of mouse brain in action., Nature methods, vol 12 no. 5 (2015), pp. 407-410 [10.1038/nmeth.3336] [abs].
  • Xia, J; Yao, J; Wang, LV, Photoacoustic tomography: principles and advances., Electromagnetic waves (Cambridge, Mass.), vol 147 (2014), pp. 1-22 [10.2528/pier14032303] [abs].
  • Wang, L; Yao, J; Maslov, KI; Xing, W; Wang, LV, Ultrasound-heated photoacoustic flowmetry., Journal of biomedical optics, vol 18 no. 11 (2013) [10.1117/1.jbo.18.11.117003] [abs].
  • Yao, J; Wang, LV, Photoacoustic Microscopy., Laser & photonics reviews, vol 7 no. 5 (2013) [10.1002/lpor.201200060] [abs].
  • Zhang, R; Yao, J; Maslov, KI; Wang, LV, Structured-illumination photoacoustic Doppler flowmetry of axial flow in homogeneous scattering media., Applied physics letters, vol 103 no. 9 (2013) [10.1063/1.4819735] [abs].
  • Zhou, Y; Yao, J; Wang, LV, Optical clearing-aided photoacoustic microscopy with enhanced resolution and imaging depth., Optics letters, vol 38 no. 14 (2013), pp. 2592-2595 [10.1364/ol.38.002592] [abs].
  • Rowland, KJ; Yao, J; Wang, L; Erwin, CR; Maslov, KI; Wang, LV; Warner, BW, Up-regulation of hypoxia-inducible factor 1 alpha and hemodynamic responses following massive small bowel resection., Journal of pediatric surgery, vol 48 no. 6 (2013), pp. 1330-1339 [10.1016/j.jpedsurg.2013.03.031] [abs].
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