R. Eugene and Susie E. Goodson Distinguished Professor of Biomedical Engineering
My research interests focus upon the effect of physical forces on the function of vascular cells and skeletal muscle, cell adhesion, and the design of engineered tissues. Current research projects examine the effect of endothelial cell senescence upon permeability to macromolecules and the response to fluid shear stress, the development of microphysiological blood vessels and muscles for evaluation of drug toxicity and the design of engineered endothelialized blood vessels and skeletal muscle bundles.
Appointments and Affiliations
- R. Eugene and Susie E. Goodson Distinguished Professor of Biomedical Engineering
- Professor of Biomedical Engineering
- Affiliate of the Duke Regeneration Center
- Affiliate of the Duke Initiative for Science & Society
Contact Information
- Office Location: 1395 Fciemas, 101 Science Drive, Durham, NC 27708-0281
- Email Address: george.truskey@duke.edu
- Websites:
Education
- B.S.E. University of Pennsylvania, 1979
- Ph.D. Massachusetts Institute of Technology, 1985
Research Interests
Cardiovascular tissue engineering, mechanisms of atherogenesis, cell adhesion, and cell biomechanics.
Awards, Honors, and Distinctions
- AAAS Fellow. American Association for the Advancement of Science. 2014
- BMES Distinguished Service Award. Biomedical Engineering Society. 2012
- NIH CSR College of Reviewers. NIH. 2010
- Capers and Marion McDonald Award for Excellence in Mentoring and Advising. Duke University. 2007
- Fellow. Biomedical Engineering Society. 2006
- Fellow. Council on Arteriosclerosis, Thrombosis and Vascular Biology, American Heart Association. 1999
- Fellow. American Institute for Medical and Biological Engineering. 1999
- Excellence in Teaching Award. Tau Beta Pi, North Carolina Gamma Chapter. 1998
- Outstanding Scientific Paper in the Journal of Parenteral Science and Technology. Parenteral Drug Association. 1987
Courses Taught
- EGR 393: Research Projects in Engineering
- BME 792: Continuation of Graduate Independent Study
- BME 791: Graduate Independent Study
- BME 590: Special Topics in Biomedical Engineering
- BME 566: Transport Phenomena in Cells and Organs (GE, MC)
- BME 494: Projects in Biomedical Engineering (GE)
- BME 493: Projects in Biomedical Engineering (GE)
- BME 493-1: Projects in Biomedical Engineering (GE)
- BME 394: Projects in Biomedical Engineering (GE)
In the News
- Duke Signs Educational Partnership With U.S. Army 18th Airborne Corps (Dec 15, …
- University Redoubles Efforts to Convert Research Into Social Impact (May 10, 20…
- An Important Step Forward in Understanding Progeria, a Rare Accelerated-Aging D…
- Big Ideas on a Small Chip Surface (Nov 1, 2019 | Pratt School of Engineering)
- Researchers have discovered a fast way to make artificial arteries for testing …
- Rapidly Building Arteries that Produce Biochemical Signals (Feb 18, 2016 | Prat…
- Grant to Support Science, Engineering Professorships for Women (Jan 14, 2016)
- Five Faculty Named Fellows of American Association for the Advancement of Scien…
Representative Publications
- Covert, Lauren T., Joseph A. Prinz, Devjanee Swain-Lenz, Jeffrey Dvergsten, and George A. Truskey. “Genetic changes from type I interferons and JAK inhibitors: clues to drivers of juvenile dermatomyositis.” Rheumatology (Oxford) 63, no. SI2 (September 1, 2024): SI240–48. https://doi.org/10.1093/rheumatology/keae082.
- Khodabukus, Alastair, Neel K. Prabhu, Taylor Roberts, Meghan Buldo, Amber Detwiler, Zachary D. Fralish, Megan E. Kondash, George A. Truskey, Timothy R. Koves, and Nenad Bursac. “Bioengineered Model of Human LGMD2B Skeletal Muscle Reveals Roles of Intracellular Calcium Overload in Contractile and Metabolic Dysfunction in Dysferlinopathy.” Adv Sci (Weinh) 11, no. 31 (August 2024): e2400188. https://doi.org/10.1002/advs.202400188.
- Lopez, Isabella, and George A. Truskey. “Multi-cellular engineered living systems to assess reproductive toxicology.” Reproductive Toxicology (Elmsford, N.Y.) 127 (August 2024): 108609. https://doi.org/10.1016/j.reprotox.2024.108609.
- Mishra, Saurabh, Nicole Welch, Shashi Shekhar Singh, Khuraijam Dhanachandra Singh, Annette Bellar, Avinash Kumar, Lars N. Deutz, et al. “Ammonia transporter RhBG initiates downstream signaling and functional responses by activating NFκB.” Proceedings of the National Academy of Sciences of the United States of America 121, no. 31 (July 2024): e2314760121. https://doi.org/10.1073/pnas.2314760121.
- Covert, Lauren T., Hailee Patel, Alaa Osman, Lavonia Duncan, Jeffrey Dvergsten, and George A. Truskey. “Effect of type I interferon on engineered pediatric skeletal muscle: a promising model for juvenile dermatomyositis.” Rheumatology (Oxford) 63, no. 1 (January 4, 2024): 209–17. https://doi.org/10.1093/rheumatology/kead186.