Walter T Lee

Professor of Head and Neck Surgery & Communication Sciences

Global Health, Virtue-Based Professional Development and Leadership, Device Development for Cancer Detection, otolaryngology, ENT, Head and Neck Cancer

Appointments and Affiliations

  • Professor of Head and Neck Surgery & Communication Sciences
  • Professor in Radiation Oncology
  • Affiliate, Duke Global Health Institute
  • Member of the Duke Cancer Institute

Contact Information

  • Office Location: 40 Medicine Circle, DUMC Box 3805, Durham, NC 27710
  • Email Address: walter.lee@duke.edu

Education

  • M.D. The George Washington University, 1999
  • M.H.S. Duke University, 2015

Courses Taught

  • HLTHPOL 796T: Bass Connections Health Policy & Innovation Research Team
  • HLTHPOL 396T: Bass Connections Health Policy & Innovation Research Team

In the News

Representative Publications

  • Lee, Walter T., Chunrui Tan, Gary Koski, Suyu Shu, and Peter Cohen. “Immunotherapy using allogeneic squamous cell tumor-dendritic cell fusion hybrids.” Head Neck 32, no. 9 (September 2010): 1209–16. https://doi.org/10.1002/hed.21323.
  • Cho, Edward I., Chunrui Tan, Gary K. Koski, Peter A. Cohen, Suyu Shu, and Walter T. Lee. “Toll-like receptor agonists as third signals for dendritic cell-tumor fusion vaccines.” Head Neck 32, no. 6 (June 2010): 700–707. https://doi.org/10.1002/hed.21241.
  • Bennett, Kristi L., Walter Lee, Eric Lamarre, Xiatong Zhang, Rahul Seth, Joseph Scharpf, Jennifer Hunt, and Charis Eng. “HPV status-independent association of alcohol and tobacco exposure or prior radiation therapy with promoter methylation of FUSSEL18, EBF3, IRX1, and SEPT9, but not SLC5A8, in head and neck squamous cell carcinomas.” Genes Chromosomes Cancer 49, no. 4 (April 2010): 319–26. https://doi.org/10.1002/gcc.20742.
  • Cannady, Steven B., Walter T. Lee, Joseph Scharpf, Robert R. Lorenz, Benjamin G. Wood, Marshall Strome, Pierre Lavertu, Ramon M. Esclamado, Jerrold P. Saxton, and David J. Adelstein. “Extent of neck dissection required after concurrent chemoradiation for stage IV head and neck squamous cell carcinoma.” Head Neck 32, no. 3 (March 2010): 348–56. https://doi.org/10.1002/hed.21189.
  • Lee, Walter T., Mark Rizzi, Joseph Scharpf, Robert R. Lorenz, Jerrod P. Saxton, David J. Adelstein, and Ramon M. Esclamado. “Impact of preepiglottic space tumor involvement on concurrent chemoradiation therapy.” Am J Otolaryngol 31, no. 3 (2010): 185–88. https://doi.org/10.1016/j.amjoto.2009.02.001.
  • Shipchandler, Taha Z., Robert R. Lorenz, Walter T. Lee, Aysenur Meric Teker, Olivia Dan, and Marshall Strome. “Laryngeal transplantation in the setting of cancer: a rat model.” Laryngoscope 118, no. 12 (December 2008): 2166–71. https://doi.org/10.1097/MLG.0b013e3181855108.
  • Lee, Walter T., Raymond R. Tubbs, Aysenur M. Teker, Joseph Scharpf, Marshall Strome, Benjamin Wood, Robert R. Lorenz, and Jennifer Hunt. “Use of in situ hybridization to detect human papillomavirus in head and neck squamous cell carcinoma patients without a history of alcohol or tobacco use.” Arch Pathol Lab Med 132, no. 10 (October 2008): 1653–56. https://doi.org/10.5858/2008-132-1653-UOISHT.
  • Lee, Walter T., Hidemasa Tamai, Peter Cohen, Aysenur Meric Teker, and Suyu Shu. “Immunotherapy of established murine squamous cell carcinoma using fused dendritic-tumor cell hybrids.” Arch Otolaryngol Head Neck Surg 134, no. 6 (June 2008): 608–13. https://doi.org/10.1001/archotol.134.6.608.
  • Zheng, Rongxiu, Peter A. Cohen, Christopher A. Paustian, Terrence D. Johnson, Walter T. Lee, Suyu Shu, and Gary K. Koski. “Paired Toll-like receptor agonists enhance vaccine therapy through induction of interleukin-12.” Cancer Research 68, no. 11 (June 2008): 4045–49. https://doi.org/10.1158/0008-5472.can-07-6669.
  • Solares, C Arturo, Walter T. Lee, Pete S. Batra, and Martin J. Citardi. “Lateral lamella of the cribriform plate: software-enabled computed tomographic analysis and its clinical relevance in skull base surgery.” Arch Otolaryngol Head Neck Surg 134, no. 3 (March 2008): 285–89. https://doi.org/10.1001/archotol.134.3.285.
  • Lorenz, Robert R., Ramon M. Esclamado, Aysenur M. Teker, Marshall Strome, Joseph Scharpf, Douglas Hicks, Claudio Milstein, and Walter T. Lee. “Ansa cervicalis-to-recurrent laryngeal nerve anastomosis for unilateral vocal fold paralysis: experience of a single institution.” Ann Otol Rhinol Laryngol 117, no. 1 (January 2008): 40–45. https://doi.org/10.1177/000348940811700109.
  • Teker, Aysenur Meric, Robert R. Lorenz, Walter T. Lee, and Sudish C. Murthy. “Radiology quiz case 1. Tracheocele.” Arch Otolaryngol Head Neck Surg, September 2007. https://doi.org/10.1001/archotol.133.9.940.
  • Garrett, Matthew M., and Walter T. Lee. “Obstructing pyogenic granuloma as a result of blunt laryngeal trauma.” Otolaryngol Head Neck Surg 136, no. 3 (March 2007): 489–90. https://doi.org/10.1016/j.otohns.2006.10.005.
  • Lee, Walter T., Claudio Milstein, Douglas Hicks, Lee M. Akst, and Ramon M. Esclamado. “Results of ansa to recurrent laryngeal nerve reinnervation.” Otolaryngol Head Neck Surg 136, no. 3 (March 2007): 450–54. https://doi.org/10.1016/j.otohns.2006.11.040.
  • Zheng, Rongxiu, Jorgen Kjaergaard, Walter T. Lee, Peter A. Cohen, and Suyu Shu. “Significance of regional draining lymph nodes in the development of tumor immunity: implications for cancer immunotherapy.” Cancer Treat Res 135 (2007): 223–37. https://doi.org/10.1007/978-0-387-69219-7_17.
  • Shu, Suyu, Rongxiu Zheng, Walter T. Lee, and Peter A. Cohen. “Immunogenicity of dendritic-tumor fusion hybrids and their utility in cancer immunotherapy.” Crit Rev Immunol 27, no. 5 (2007): 463–83. https://doi.org/10.1615/critrevimmunol.v27.i5.50.
  • Cho, Jae Hoon, Martin J. Citardi, Walter T. Lee, Nathan B. Sautter, Heung-Man Lee, Joo-Heon Yoon, Seok-Chan Hong, and Jin Kook Kim. “Comparison of frontal pneumatization patterns between Koreans and Caucasians.” Otolaryngol Head Neck Surg 135, no. 5 (November 2006): 780–86. https://doi.org/10.1016/j.otohns.2006.05.750.
  • Lee, Walter T., Lee M. Akst, David J. Adelstein, Jerrod P. Saxton, Benjamin G. Wood, Marshall Strome, Robert S. Butler, and Ramon M. Esclamado. “Risk factors for hypopharyngeal/upper esophageal stricture formation after concurrent chemoradiation.” Head Neck 28, no. 9 (September 2006): 808–12. https://doi.org/10.1002/hed.20427.
  • Lee, Walter T., Ron Eliashar, and Isaac Eliachar. “Acute external laryngotracheal trauma: diagnosis and management.” Ear Nose Throat J 85, no. 3 (March 2006): 179–84.
  • Lee, Walter T., Sudish C. Murthy, Thomas R. Gildea, and Robert R. Lorenz. “First case of laryngeal glomangiomyoma.” Laryngoscope 115, no. 11 (November 2005): 2038–40. https://doi.org/10.1097/01.mlg.0000177097.19336.eb.
  • Lee, Walter T., Keiji Shimizu, Hide Kuriyama, Hiro Tanaka, Jorgen Kjaergaard, and Suyu Shu. “Tumor-dendritic cell fusion as a basis for cancer immunotherapy.” Otolaryngol Head Neck Surg 132, no. 5 (May 2005): 755–64. https://doi.org/10.1016/j.otohns.2005.01.018.
  • Khariwala, Samir S., Walter T. Lee, and Peter J. Koltai. “Laryngotracheal consequences of pediatric cardiac surgery.” Arch Otolaryngol Head Neck Surg 131, no. 4 (April 2005): 336–39. https://doi.org/10.1001/archotol.131.4.336.
  • Lee, Walter T., and Peter C. Weber. “Melanoma metastasis masquerading as bilateral acoustic neuromas.” Otolaryngol Head Neck Surg 132, no. 3 (March 2005): 505–6. https://doi.org/10.1016/j.otohns.2004.05.004.
  • Lee, Walter T., Frederick A. Kuhn, and Martin J. Citardi. “3D computed tomographic analysis of frontal recess anatomy in patients without frontal sinusitis.” Otolaryngol Head Neck Surg 131, no. 3 (September 2004): 164–73. https://doi.org/10.1016/j.otohns.2004.04.012.
  • Shimizu, Keiji, Hideyuki Kuriyama, Jorgen Kjaergaard, Walter Lee, Hiroshi Tanaka, and Suyu Shu. “Comparative analysis of antigen loading strategies of dendritic cells for tumor immunotherapy.” J Immunother 27, no. 4 (2004): 265–72. https://doi.org/10.1097/00002371-200407000-00002.
  • Akst, Lee M., Walter Lee, Christopher Discolo, Daniel Knott, Abbas Younes, and Peter J. Koltai. “Stepped-dose protocol of cidofovir therapy in recurrent respiratory papillomatosis in children.” Arch Otolaryngol Head Neck Surg 129, no. 8 (August 2003): 841–46. https://doi.org/10.1001/archotol.129.8.841.
  • Lee, Walter T., and Peter J. Koltai. “Nasal deformity in neonates and young children.” Pediatr Clin North Am 50, no. 2 (April 2003): 459–67. https://doi.org/10.1016/s0031-3955(03)00036-1.
  • Lee, Walter, Peter Koltai, A Marc Harrison, Elumalai Appachi, Demetrios Bourdakos, Steve Davis, Kathryn Weise, Michael McHugh, and Jason Connor. “Indications for tracheotomy in the pediatric intensive care unit population: a pilot study.” Arch Otolaryngol Head Neck Surg 128, no. 11 (November 2002): 1249–52. https://doi.org/10.1001/archotol.128.11.1249.