Walter T Lee


Professor of Head and Neck Surgery & Communication Sciences

Global Health, Virtue-Based Professional Development and Leadership, Device Development for Cancer Detection, otolaryngology, ENT, Head and Neck Cancer

Appointments and Affiliations

  • Professor of Head and Neck Surgery & Communication Sciences
  • Professor in Radiation Oncology
  • Affiliate, Duke Global Health Institute
  • Member of the Duke Cancer Institute

Contact Information

  • Office Location: 40 Medicine Circle, DUMC Box 3805, Durham, NC 27710
  • Office Phone: +1 919 681 6820
  • Email Address:


  • M.H.S. Duke University, 2015
  • M.D. The George Washington University, 1999

Courses Taught

  • HLTHPOL 796T: Bass Connections Health Policy & Innovation Research Team
  • HLTHPOL 396T: Bass Connections Health Policy & Innovation Research Team

In the News

Representative Publications

  • Lee, WT; Tan, C; Koski, G; Shu, S; Cohen, P, Immunotherapy using allogeneic squamous cell tumor-dendritic cell fusion hybrids., Head Neck, vol 32 no. 9 (2010), pp. 1209-1216 [10.1002/hed.21323] [abs].
  • Cho, EI; Tan, C; Koski, GK; Cohen, PA; Shu, S; Lee, WT, Toll-like receptor agonists as third signals for dendritic cell-tumor fusion vaccines., Head Neck, vol 32 no. 6 (2010), pp. 700-707 [10.1002/hed.21241] [abs].
  • Bennett, KL; Lee, W; Lamarre, E; Zhang, X; Seth, R; Scharpf, J; Hunt, J; Eng, C, HPV status-independent association of alcohol and tobacco exposure or prior radiation therapy with promoter methylation of FUSSEL18, EBF3, IRX1, and SEPT9, but not SLC5A8, in head and neck squamous cell carcinomas., Genes Chromosomes Cancer, vol 49 no. 4 (2010), pp. 319-326 [10.1002/gcc.20742] [abs].
  • Cannady, SB; Lee, WT; Scharpf, J; Lorenz, RR; Wood, BG; Strome, M; Lavertu, P; Esclamado, RM; Saxton, JP; Adelstein, DJ, Extent of neck dissection required after concurrent chemoradiation for stage IV head and neck squamous cell carcinoma., Head Neck, vol 32 no. 3 (2010), pp. 348-356 [10.1002/hed.21189] [abs].
  • Lee, WT; Rizzi, M; Scharpf, J; Lorenz, RR; Saxton, JP; Adelstein, DJ; Esclamado, RM, Impact of preepiglottic space tumor involvement on concurrent chemoradiation therapy., Am J Otolaryngol, vol 31 no. 3 (2010), pp. 185-188 [10.1016/j.amjoto.2009.02.001] [abs].
  • Shipchandler, TZ; Lorenz, RR; Lee, WT; Teker, AM; Dan, O; Strome, M, Laryngeal transplantation in the setting of cancer: a rat model., Laryngoscope, vol 118 no. 12 (2008), pp. 2166-2171 [10.1097/MLG.0b013e3181855108] [abs].
  • Lee, WT; Tubbs, RR; Teker, AM; Scharpf, J; Strome, M; Wood, B; Lorenz, RR; Hunt, J, Use of in situ hybridization to detect human papillomavirus in head and neck squamous cell carcinoma patients without a history of alcohol or tobacco use., Arch Pathol Lab Med, vol 132 no. 10 (2008), pp. 1653-1656 [10.5858/2008-132-1653-UOISHT] [abs].
  • Lee, WT; Tamai, H; Cohen, P; Teker, AM; Shu, S, Immunotherapy of established murine squamous cell carcinoma using fused dendritic-tumor cell hybrids., Arch Otolaryngol Head Neck Surg, vol 134 no. 6 (2008), pp. 608-613 [10.1001/archotol.134.6.608] [abs].
  • Zheng, R; Cohen, PA; Paustian, CA; Johnson, TD; Lee, WT; Shu, S; Koski, GK, Paired Toll-like receptor agonists enhance vaccine therapy through induction of interleukin-12., Cancer research, vol 68 no. 11 (2008), pp. 4045-4049 [10.1158/0008-5472.can-07-6669] [abs].
  • Solares, CA; Lee, WT; Batra, PS; Citardi, MJ, Lateral lamella of the cribriform plate: software-enabled computed tomographic analysis and its clinical relevance in skull base surgery., Arch Otolaryngol Head Neck Surg, vol 134 no. 3 (2008), pp. 285-289 [10.1001/archotol.134.3.285] [abs].
  • Lorenz, RR; Esclamado, RM; Teker, AM; Strome, M; Scharpf, J; Hicks, D; Milstein, C; Lee, WT, Ansa cervicalis-to-recurrent laryngeal nerve anastomosis for unilateral vocal fold paralysis: experience of a single institution., Ann Otol Rhinol Laryngol, vol 117 no. 1 (2008), pp. 40-45 [10.1177/000348940811700109] [abs].
  • Teker, AM; Lorenz, RR; Lee, WT; Murthy, SC, Radiology quiz case 1. Tracheocele., Arch Otolaryngol Head Neck Surg, vol 133 no. 9 (2007), pp. 940-943 [10.1001/archotol.133.9.940] [abs].
  • Garrett, MM; Lee, WT, Obstructing pyogenic granuloma as a result of blunt laryngeal trauma., Otolaryngol Head Neck Surg, vol 136 no. 3 (2007), pp. 489-490 [10.1016/j.otohns.2006.10.005] [abs].
  • Lee, WT; Milstein, C; Hicks, D; Akst, LM; Esclamado, RM, Results of ansa to recurrent laryngeal nerve reinnervation., Otolaryngol Head Neck Surg, vol 136 no. 3 (2007), pp. 450-454 [10.1016/j.otohns.2006.11.040] [abs].
  • Shu, S; Zheng, R; Lee, WT; Cohen, PA, Immunogenicity of dendritic-tumor fusion hybrids and their utility in cancer immunotherapy., Crit Rev Immunol, vol 27 no. 5 (2007), pp. 463-483 [10.1615/critrevimmunol.v27.i5.50] [abs].
  • Zheng, R; Kjaergaard, J; Lee, WT; Cohen, PA; Shu, S, Significance of regional draining lymph nodes in the development of tumor immunity: implications for cancer immunotherapy., Cancer Treat Res, vol 135 (2007), pp. 223-237 [10.1007/978-0-387-69219-7_17] [abs].
  • Cho, JH; Citardi, MJ; Lee, WT; Sautter, NB; Lee, H-M; Yoon, J-H; Hong, S-C; Kim, JK, Comparison of frontal pneumatization patterns between Koreans and Caucasians., Otolaryngol Head Neck Surg, vol 135 no. 5 (2006), pp. 780-786 [10.1016/j.otohns.2006.05.750] [abs].
  • Lee, WT; Akst, LM; Adelstein, DJ; Saxton, JP; Wood, BG; Strome, M; Butler, RS; Esclamado, RM, Risk factors for hypopharyngeal/upper esophageal stricture formation after concurrent chemoradiation., Head Neck, vol 28 no. 9 (2006), pp. 808-812 [10.1002/hed.20427] [abs].
  • Lee, WT; Eliashar, R; Eliachar, I, Acute external laryngotracheal trauma: diagnosis and management., Ear Nose Throat J, vol 85 no. 3 (2006), pp. 179-184 [abs].
  • Lee, WT; Murthy, SC; Gildea, TR; Lorenz, RR, First case of laryngeal glomangiomyoma., Laryngoscope, vol 115 no. 11 (2005), pp. 2038-2040 [10.1097/01.mlg.0000177097.19336.eb] [abs].
  • Lee, WT; Shimizu, K; Kuriyama, H; Tanaka, H; Kjaergaard, J; Shu, S, Tumor-dendritic cell fusion as a basis for cancer immunotherapy., Otolaryngol Head Neck Surg, vol 132 no. 5 (2005), pp. 755-764 [10.1016/j.otohns.2005.01.018] [abs].
  • Khariwala, SS; Lee, WT; Koltai, PJ, Laryngotracheal consequences of pediatric cardiac surgery., Arch Otolaryngol Head Neck Surg, vol 131 no. 4 (2005), pp. 336-339 [10.1001/archotol.131.4.336] [abs].
  • Lee, WT; Weber, PC, Melanoma metastasis masquerading as bilateral acoustic neuromas., Otolaryngol Head Neck Surg, vol 132 no. 3 (2005), pp. 505-506 [10.1016/j.otohns.2004.05.004] [abs].
  • Lee, WT; Kuhn, FA; Citardi, MJ, 3D computed tomographic analysis of frontal recess anatomy in patients without frontal sinusitis., Otolaryngol Head Neck Surg, vol 131 no. 3 (2004), pp. 164-173 [10.1016/j.otohns.2004.04.012] [abs].
  • Shimizu, K; Kuriyama, H; Kjaergaard, J; Lee, W; Tanaka, H; Shu, S, Comparative analysis of antigen loading strategies of dendritic cells for tumor immunotherapy., J Immunother, vol 27 no. 4 (2004), pp. 265-272 [10.1097/00002371-200407000-00002] [abs].
  • Akst, LM; Lee, W; Discolo, C; Knott, D; Younes, A; Koltai, PJ, Stepped-dose protocol of cidofovir therapy in recurrent respiratory papillomatosis in children., Arch Otolaryngol Head Neck Surg, vol 129 no. 8 (2003), pp. 841-846 [10.1001/archotol.129.8.841] [abs].
  • Lee, WT; Koltai, PJ, Nasal deformity in neonates and young children., Pediatr Clin North Am, vol 50 no. 2 (2003), pp. 459-467 [10.1016/s0031-3955(03)00036-1] [abs].
  • Lee, W; Koltai, P; Harrison, AM; Appachi, E; Bourdakos, D; Davis, S; Weise, K; McHugh, M; Connor, J, Indications for tracheotomy in the pediatric intensive care unit population: a pilot study., Arch Otolaryngol Head Neck Surg, vol 128 no. 11 (2002), pp. 1249-1252 [10.1001/archotol.128.11.1249] [abs].