Systems Modeling Techniques Theory & Data Treatment

Advanced photonic techniques using ultrafast lasers, multi-photon, time-resolved and phase-resolved detection techniques, polarization and lifetime measurements further extend the usefulness of molecular and cell-based assays.

Another important advance in photonic technologies is the development of advanced imaging systems that have the combined capability of high-resolution, high-throughput and multi-spectral detection of optical reporters. Near-field spectroscopies provide important tools to investigate and develop new classes of molecular and cellular labels based on inorganic fluorophors, second-generation quantum dots, and plasmonics nanoprobes. Single-molecule detection techniques using various photonics modalities provide the ultimate tools to elucidate cellular processes at the molecular level.

Another area of research focus involves novel photonics platforms for ultra-high throughput assays and diagnostics and therapy in personalized medicine. 

A new research area involves the so-called "Terahertz (THz) gap", which refers to the region of the electromagnetic spectrum that lies between microwave and infrared wavelengths. Due to the difficulties involved in making reliable THz sources and detectors, the terahertz frequency range still remains one of the least explored regions of the electromagnetic spectrum. However, this regime is rich with possibilities in spectroscopy and imaging.

We will also form a team of theoretical investigators in systems modeling and medical data treatment, who will be developing the much needed mathematical models for deep tissue imaging and image construction.

Other important theoretical areas involve bioinformatics, biomolecular computing, and theoretical modeling of self assembly of DNA nanostructures and photonic nanosystems.

Systems Modeling Theory Data Treatment Faculty

David N. Beratan

R.J. Reynolds Professor of Chemistry
Dr. Beratan is developing theoretical approaches to understand the function of complex molecular and macromolecular systems, including: the molecular...

Volker Blum

Associate Professor in the Department of Mechanical Engineering and Materials Science
Volker Blum heads the "Ab initio materials simulations" group at Duke University. Dr. Blum's research focuses on "first-principles" computational...

Leslie M. Collins

Professor of Electrical and Computer Engineering
Leslie M. Collins earned the BSEE degree from the University of Kentucky, and the MSEE, and PhD degrees from the University of Michigan, Ann Arbor....

Richard T. Di Giulio

Professor of Environmental Toxicology
Dr. Di Giulio serves as Director of Duke University's Integrated Toxicology Program and the Superfund Basic Research Center. Dr. Di Giulio's...

Anna Mae Diehl

Florence McAlister Professor of Medicine, in the School of Medicine
Our lab has a long standing interest in liver injury and repair. To learn more about the mechanisms that regulate this process, we study cultured...

Christopher Dwyer

Associate Professor in the Department of Electrical and Computer Engineering
Dr. Chris Dwyer received his B.S. in computer engineering from the Pennsylvania State University in 1998, and his M.S. and Ph.D. in computer science...

Sina Farsiu

Associate Professor in the Department of Biomedical Engineering
I am the director of the Vision and Image Processing (VIP) Laboratory. Along with my colleagues, we investigate how to improve early diagnostic...

Silvia Ferrari

Adjunct Professor in the Department of Mechanical Engineering and Materials Science

Jeffrey L. Krolik

Professor of Electrical and Computer Engineering
Jeffrey Krolik is Professor of Electrical and Computer Engineering at Duke University in Durham, NC. Canadian-born, he received his Ph.D. in...

Qing Huo Liu

Professor of Electrical and Computer Engineering
Qing H. Liu received the Ph.D. degree in electrical engineering from the University of Illinois at Urbana-Champaign in 1989. His research interests...

Jianfeng Lu

Associate Professor of Mathematics
Jianfeng Lu is an applied mathematician interested in mathematical analysis and algorithm development for problems from computational physics,...

Miroslav Pajic

Assistant Professor in the Department of Electrical and Computer Engineering
Miroslav Pajic's research focuses on design and analysis of cyber-physical systems and in particular, embedded and distributed/networked control...

Niko P. Pitsianis

Adjunct Professor of Computer Science
Nikos Pitsianis' research experience and interests are in algorithms and architectures for high performance computing, numerical linear algebra and...

Guillermo Sapiro

Edmund T. Pratt, Jr. School Professor of Electrical and Computer Engineering
Guillermo Sapiro received his B.Sc. (summa cum laude), M.Sc., and Ph.D. from the Department of Electrical Engineering at the Technion, Israel...

Xiaobai Sun

Professor of Computer Science

Stephanos Venakides

Professor of Mathematics
Integrable Systems Integrable systems mostly consist of families of nonlinear differential equations (ordinary and partial) that can be solved (...

Weitao Yang

Philip Handler Professor of Chemistry in Trinity College of Arts and Sciences
Prof. Yang, the Philip Handler Professor of Chemistry, is developing methods for quantum mechanical calculations of large systems and carrying out...