Greg D. Field
Adjunct Associate Professor of Neurobiology
My laboratory studies how the retina processes visual scenes and transmits this information to the brain. We use multi-electrode arrays to record the activity of hundreds of retina neurons simultaneously in conjunction with transgenic mouse lines and chemogenetics to manipulate neural circuit function. We are interested in three major areas. First, we work to understand how neurons in the retina are functionally connected. Second we are studying how light-adaptation and circadian rhythms alter visual processing in the retina. Finally, we are working to understand the mechanisms of retinal degenerative conditions and we are investigating potential treatments in animal models.
Appointments and Affiliations
- Adjunct Associate Professor of Neurobiology
- Faculty Network Member of the Duke Institute for Brain Sciences
Contact Information
- Office Location: Bryan Research Building, 311 Research Drive Room 427D, Durham, NC 27710
- Office Phone: +1 919 681 7503
- Email Address: field@neuro.duke.edu
Education
- Ph.D. University of Washington, 2004
Courses Taught
- NEUROSCI 495: Research Independent Study 3
- NEUROSCI 494: Research Independent Study 2
- NEUROBIO 793: Research in Neurobiology
In the News
- Living Retina Achieves Sensitivity and Efficiency Engineers Can Only Dream About (Sep 28, 2021)
- Real Neurons are Noisy. Can Neural Implants Figure That Out? (Sep 15, 2020)
- Eyes Have a Natural Version of Night Vision (Sep 13, 2018)
Representative Publications
- Fleming, EA; Field, GD; Tadross, MR; Hull, C, Local synaptic inhibition mediates cerebellar granule cell pattern separation and enables learned sensorimotor associations., Nat Neurosci, vol 27 no. 4 (2024), pp. 689-701 [10.1038/s41593-023-01565-4] [abs].
- Roy, S; Yao, X; Rathinavelu, J; Field, GD, GABAergic Inhibition Controls Receptive Field Size, Sensitivity, and Contrast Preference of Direction Selective Retinal Ganglion Cells Near the Threshold of Vision., J Neurosci, vol 44 no. 11 (2024) [10.1523/JNEUROSCI.1979-23.2023] [abs].
- Dyballa, L; Rudzite, AM; Hoseini, MS; Thapa, M; Stryker, MP; Field, GD; Zucker, SW, Population encoding of stimulus features along the visual hierarchy., Proc Natl Acad Sci U S A, vol 121 no. 4 (2024) [10.1073/pnas.2317773121] [abs].
- Scalabrino, ML; Thapa, M; Wang, T; Sampath, AP; Chen, J; Field, GD, Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa., Nat Commun, vol 14 no. 1 (2023) [10.1038/s41467-023-44063-8] [abs].
- Wu, EG; Rudzite, AM; Bohlen, MO; Li, PH; Kling, A; Cooler, S; Rhoades, C; Brackbill, N; Gogliettino, AR; Shah, NP; Madugula, SS; Sher, A; Litke, AM; Field, GD; Chichilnisky, EJ, Decomposition of retinal ganglion cell electrical images for cell type and functional inference., bioRxiv (2023) [10.1101/2023.11.06.565889] [abs].