Amanda Randles

Alfred Winborne and Victoria Stover Mordecai Associate Professor of Biomedical Sciences

My research in biomedical simulation and high-performance computing focuses on the development of new computational tools that we use to provide insight into the localization and development of human diseases ranging from atherosclerosis to cancer. 

Appointments and Affiliations

• Alfred Winborne and Victoria Stover Mordecai Associate Professor of Biomedical Sciences
• Associate Professor of Biomedical Engineering
• Assistant Professor in the Thomas Lord Department of Mechanical Engineering and Materials Science
• Assistant Professor of Computer Science
• Member of the Duke Cancer Institute

Contact Information

• Office Location: Wilkinson Building, Room No. 325, 534 Research Drive, Durham, NC 27708
• Office Phone: (919) 660-6962
• Email Address: amanda.randles@duke.edu
• Websites:
  • Google Scholar
  • Randles Lab Site

Education

• Ph.D. Harvard University , 2013

Research Interests

Biomedical simulation and high-performance computing

Awards, Honors, and Distinctions

• Stansell Family Distinguished Research Award. Pratt School of Engineering. 2023
• Pioneer Award. NIH. 2022
• Fellow (NAI). National Academy of Inventors. 2021
• Fellow. National Academy of Inventors. 2021
• Senior Member. National Academy of Inventors. 2019
• IEEE-CS Technical Consortium on High Performance Computing (TCHPC) Award for Excellence for Early Career Researchers in High Performance Computing. IEEE. 2017
• Grace Murray Hopper Award. ACM. 2017
• MIT TR35 Visionary. MIT TR35. 2017
• Ralph E. Powe Junior Faculty Enhancement Award. Oak Ridge Associated Universities. 2016
• Best Paper, IEEE International Conference on Computational Science (ICCS) 2015. IEEE. 2015
• Gordon Bell Finalist. ACM. 2015
• Early Independence Award. NIH. 2014
• Lawrence Fellowship. Lawrence Livermore National Laboratory. 2013
• U.S. Delegate . Heidelberg Laureate Forum. 2013
• Anita Borg Memorial Scholarship. Google. 2012
• George Michael Memorial High Performance Computing Fellowship. ACM/IEEE. 2012
• U.S. Delegate . Lindau Nobel Laureates and Students Meeting Dedicated to Physics. 2012
• Computational Science Graduate Fellowship. Department of Energy. 2010
• George Michael Memorial High Performance Computing Fellowship. ACM/IEEE. 2010
• Gordon Bell Finalist. ACM. 2010
• Graduate Research Fellowship. National Science Foundation. 2009

Courses Taught

• BME 307: Transport Phenomena in Biological Systems (AC or GE, BB)
• BME 493: Projects in Biomedical Engineering (GE)
• BME 590L: Special Topics with Lab
• BME 791: Graduate Independent Study
• BME 792: Continuation of Graduate Independent Study
• EGR 393: Research Projects in Engineering

In the News

• Two Duke Faculty Have Won the NIH’s Prestigious Pioneer Award (Oct 3, 2022)
• Randles Elected Fellow of National Academy of Inventors (Dec 8, 2021 | Duke Engineering News)
• The Race to Split a Ventilator (Dec 9, 2020)
• Virtual Reality Blood Flow Simulation To Improve Cardiovascular Interventions (May 14, 2020 | Pratt School of Engineering)
• Randles' Cancer Simulations Aims to Be Critical Step Toward Understanding Cancer Metastasis (Sep 11, 2019 | Duke Cancer Institute)
• A Revolutionary Picture of Blood Flow Opens New Avenues for Disease Diagnosis and Treatment (Aug 8, 2019 | Pratt School of Engineering)
• Randles Selected to Help Pilot First U.S. Exascale Computer (Jul 6, 2018 | Pratt School of Engineering)
• Duke University Models How and Where Blood flow Impacts Health (Nov 1, 2017)
• Plumbing Virtual Vessels (Sep 21, 2017)
• Supercomputer copies whole-body blood flow (Mar 17, 2016 | BBC News)
• New Collaborative Seed Grant Program Gives Eight Awards (Mar 16, 2016)
• NIH Features Randles Research on Fighting Cancer With Supercomputers (Nov 19, 2015 | Duke Today)
• Experts put health issues firmly in the spotlight (Sep 14, 2015 | China Daily)
• Amanda Randles: Computing Complex Biological Systems (Jun 5, 2015 | Pratt School of Engineering)

Representative Publications

• Feiger, B; Jensen, CW; Bryner, BS; Segars, WP; Randles, A, Modeling the effect of patient size on cerebral perfusion during veno-arterial extracorporeal membrane oxygenation., Perfusion (2023) [10.1177/02676591231187962] [abs].
• Roychowdhury, S; Draeger, EW; Randles, A, Establishing metrics to quantify spatial similarity in spherical and red blood cell distributions, Journal of Computational Science, vol 71 (2023) [10.1016/j.jocs.2023.102060] [abs].
• Tanade, C; Putney, S; Randles, A, Establishing massively parallel models to examine the influence of cell heterogeneity on tumor growth, Journal of Computational Science, vol 71 (2023) [10.1016/j.jocs.2023.102059] [abs].
• Shi, H; Vardhan, M; Randles, A, The Role of Immersion for Improving Extended Reality Analysis of Personalized Flow Simulations., Cardiovascular Engineering and Technology, vol 14 no. 2 (2023), pp. 194-203 [10.1007/s13239-022-00646-y] [abs].
• Pepona, M; Gounley, J; Randles, A, Effect of constitutive law on the erythrocyte membrane response to large strains, Computers & Mathematics With Applications, vol 132 (2023), pp. 145-160 [10.1016/j.camwa.2022.12.009] [abs].