Associate Professor of Biochemistry
Appointments and Affiliations
- Associate Professor of Biochemistry
- Associate Professor of Biomedical Engineering
- Associate Professor in Neurobiology
- Associate Professor in Medicine
- Assistant Professor of Cell Biology
- Faculty Network Member of the Duke Institute for Brain Sciences
Contact Information
- Office Location: 213 Nanaline H Duke, Box 3711, DUMC, Durham, NC 27710
- Email Address: huanghe.yang@duke.edu
- Websites:
Education
- Ph.D. Washington University in St. Louis, 2008
Awards, Honors, and Distinctions
- NIH Director's New Innovator Award. NIH. 2017
- Pathway to Independence Award (K99/R00). NINDS. 2014
Courses Taught
- BIOCHEM 593: Research Independent Study
- BIOCHEM 393: Research Independent Study
In the News
Representative Publications
- Liang, Pengfei, Yui-Chun S. Wan, Ke Z. Shan, Ryan Chou, Yang Zhang, Martha Delahunty, Sanjay Khandelwal, et al. “Targeting PIEZO1-TMEM16F Coupling to Mitigate Sickle Cell Disease Complications.” Am J Hematol 100, no. 12 (December 2025): 2261–75. https://doi.org/10.1002/ajh.70086.
- Zheng, Wang, Augustus J. Lowry, Harper E. Smith, Jiale Xie, Shaun Rawson, Chen Wang, Jin Ou, et al. “Structural and functional basis of mechanosensitive TMEM63 channelopathies.” Neuron 113, no. 15 (August 6, 2025): 2474-2489.e5. https://doi.org/10.1016/j.neuron.2025.05.009.
- Zhang, Yang, Ke Z. Shan, Pengfei Liang, Augustus J. Lowry, Liping Feng, and Huanghe Yang. “PIEZO1 drives trophoblast fusion and placental development.” Nat Commun 16, no. 1 (July 26, 2025): 6895. https://doi.org/10.1038/s41467-025-62254-3.
- Liang, Pengfei, Yui-Chun Serena Wan, Ke Zoe Shan, Ryan Chou, Yang Zhang, Martha Delahunty, Sanjay Khandelwal, et al. “Targeting PIEZO1-TMEM16F Coupling to Mitigate Sickle Cell Disease Complications.” BioRxiv, May 31, 2025. https://doi.org/10.1101/2025.05.27.656389.
- Zhang, Yang, Ke Z. Shan, Pengfei Liang, Augustus J. Lowry, Liping Feng, and Huanghe Yang. “PIEZO1 Drives Trophoblast Fusion and Placental Development.” BioRxiv, March 26, 2025. https://doi.org/10.1101/2025.03.25.645313.