Huanghe Yang


Assistant Professor of Biochemistry

Appointments and Affiliations

  • Assistant Professor of Biochemistry
  • Assistant Professor in Neurobiology
  • Faculty Network Member of the Duke Institute for Brain Sciences

Contact Information

  • Office Location: 151 Nanaline H Duke, Box 3711, DUMC, Durham, NC 27710
  • Office Phone: (919) 684-1406
  • Email Address:
  • Websites:


  • Ph.D. Washington University in St. Louis, 2008

Awards, Honors, and Distinctions

  • NIH Director's New Innovator Award. NIH. 2017
  • Pathway to Independence Award (K99/R00). NINDS. 2014

Courses Taught

  • BIOCHEM 393: Research Independent Study
  • BIOCHEM 593: Research Independent Study
  • NEUROBIO 793: Research in Neurobiology

In the News

Representative Publications

  • Le, SC; Jia, Z; Chen, J; Yang, H, Molecular basis of PIP2-dependent regulation of the Ca2+-activated chloride channel TMEM16A., Nature Communications, vol 10 no. 1 (2019) [10.1038/s41467-019-11784-8] [abs].
  • Zhang, Y; Yang, H, Corrigendum to "A simple and robust fluorescent labeling method to quantify trophoblast fusion" [Placenta 77 (2019) 16-18]., Placenta, vol 82 (2019) [10.1016/j.placenta.2019.05.011] [abs].
  • Le, T; Jia, Z; Le, SC; Zhang, Y; Chen, J; Yang, H, An inner activation gate controls TMEM16F phospholipid scrambling., Nature Communications, vol 10 no. 1 (2019) [10.1038/s41467-019-09778-7] [abs].
  • Le, T; Le, SC; Yang, H, Drosophila Subdued is a moonlighting transmembrane protein 16 (TMEM16) that transports ions and phospholipids., The Journal of Biological Chemistry, vol 294 no. 12 (2019), pp. 4529-4537 [10.1074/jbc.AC118.006530] [abs].
  • Yin, Y; Le, SC; Hsu, AL; Borgnia, MJ; Yang, H; Lee, S-Y, Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel., Science, vol 363 no. 6430 (2019) [10.1126/science.aav9334] [abs].