Huanghe Yang


Associate Professor of Biochemistry

Appointments and Affiliations

  • Associate Professor of Biochemistry
  • Assistant Professor in Neurobiology
  • Assistant Professor of Cell Biology
  • Faculty Network Member of the Duke Institute for Brain Sciences

Contact Information

  • Office Location: 213 Nanaline H Duke, Box 3711, DUMC, Durham, NC 27710
  • Office Phone: (919) 684-1406
  • Email Address:
  • Websites:


  • Ph.D. Washington University in St. Louis, 2008

Awards, Honors, and Distinctions

  • NIH Director's New Innovator Award. NIH. 2017
  • Pathway to Independence Award (K99/R00). NINDS. 2014

Courses Taught

  • BIOCHEM 393: Research Independent Study
  • BIOCHEM 593: Research Independent Study
  • NEUROBIO 393: Research Independent Study
  • NEUROBIO 793: Research in Neurobiology

In the News

Representative Publications

  • Yang, L; Liang, P; Yang, H; Coyne, CB, Trophoblast organoids with physiological polarity model placental structure and function. (2023) [10.1101/2023.01.12.523752] [abs].
  • Zhang, Y; Liang, P; Yang, L; Shan, KZ; Feng, L; Chen, Y; Liedtke, W; Coyne, CB; Yang, H, Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion., Elife, vol 11 (2022) [10.7554/eLife.78840] [abs].
  • Dong, P; Zhang, Y; Hunanyan, AS; Mikati, MA; Cui, J; Yang, H, Neuronal mechanism of a BK channelopathy in absence epilepsy and dyskinesia., Proc Natl Acad Sci U S A, vol 119 no. 12 (2022) [10.1073/pnas.2200140119] [abs].
  • Chen, Y; Wang, Z-L; Yeo, M; Zhang, Q-J; López-Romero, AE; Ding, H-P; Zhang, X; Zeng, Q; Morales-Lázaro, SL; Moore, C; Jin, Y-A; Yang, H-H; Morstein, J; Bortsov, A; Krawczyk, M; Lammert, F; Abdelmalek, M; Diehl, AM; Milkiewicz, P; Kremer, AE; Zhang, JY; Nackley, A; Reeves, TE; Ko, M-C; Ji, R-R; Rosenbaum, T; Liedtke, W, Epithelia-Sensory Neuron Cross Talk Underlies Cholestatic Itch Induced by Lysophosphatidylcholine., Gastroenterology, vol 161 no. 1 (2021), pp. 301-317.e16 [10.1053/j.gastro.2021.03.049] [abs].
  • Liang, P; Yang, H, Molecular underpinning of intracellular pH regulation on TMEM16F., J Gen Physiol, vol 153 no. 2 (2021) [10.1085/jgp.202012704] [abs].