Associate Professor of Biochemistry
Appointments and Affiliations
- Associate Professor of Biochemistry
- Assistant Professor of Cell Biology
- Associate Professor in Medicine
- Associate Professor in Neurobiology
- Associate Professor of Biomedical Engineering
- Associate Professor in Obstetrics and Gynecology
- Faculty Network Member of the Duke Institute for Brain Sciences
Contact Information
- Office Location: 213 Nanaline H Duke, Box 3711, DUMC, Durham, NC 27710
- Email Address: huanghe.yang@duke.edu
- Websites:
Education
- Ph.D. Washington University in St. Louis, 2008
Awards, Honors, and Distinctions
- NIH Director's New Innovator Award. NIH. 2017
- Pathway to Independence Award (K99/R00). NINDS. 2014
Courses Taught
- BIOCHEM 593: Research Independent Study
- BIOCHEM 393: Research Independent Study
In the News
Representative Publications
- Zhang, Qiaojuan, Shanchun Su, Pengfei Liang, Yun Chen, Minseok Kim, Robert Baldi, Peng Wang, et al. “LPA/LPAR signaling drives temporomandibular disorders-like pain through regulating the expression and sensitization of PIEZO2.” Sci Adv 12, no. 30 (July 24, 2026): eaed1854. https://doi.org/10.1126/sciadv.aed1854.
- Liang, Pengfei, Yui-Chun Serena Wan, Ke Zoe Shan, Yang Zhang, Martha Delahunty, Sanjay Khandelwal, Gowthami Arepally, Marilyn Telen, and Huanghe Yang. “Cannabidiol Inhibits PIEZO Channels to Mitigate Red Blood Disorders.” BioRxiv, 2026. https://doi.org/10.64898/2026.01.22.700543.
- Wan, Yui Chun Serena, Martha Delahunty, Grace Lee, Sanjay Khandelwal, Gowthami Arepally, Marilyn Telen, and Huanghe Yang. “Gardos potassium channel amplifies PIEZO1-TMEM16F coupling in red blood cells.” BioRxiv, 2026. https://doi.org/10.64898/2026.05.28.728404.
- Liang, Pengfei, Yui-Chun S. Wan, Ke Z. Shan, Ryan Chou, Yang Zhang, Martha Delahunty, Sanjay Khandelwal, et al. “Targeting PIEZO1-TMEM16F Coupling to Mitigate Sickle Cell Disease Complications.” Am J Hematol 100, no. 12 (December 2025): 2261–75. https://doi.org/10.1002/ajh.70086.
- Zheng, Wang, Augustus J. Lowry, Harper E. Smith, Jiale Xie, Shaun Rawson, Chen Wang, Jin Ou, et al. “Structural and functional basis of mechanosensitive TMEM63 channelopathies.” Neuron 113, no. 15 (August 6, 2025): 2474-2489.e5. https://doi.org/10.1016/j.neuron.2025.05.009.