Jennifer Lyn Roizen

Roizen

Assistant Professor of Chemistry

Inspired by small molecule natural products, the Roizen laboratories will initiate research to access improved antibiotics, and selective ion channel inhibitors, with implications for the study and treatment of cancer, heart disease, and neurological disorders. This program will begin with the development of novel reaction methods, and where appropriate these methodologies will be advanced through mechanistic investigations. New reactions will be designed to streamline access to challenging natural products, such as the guaianolide sesquiterpenes. Access to these small molecules will enable us to collaborate with colleagues to probe the biological activity of these molecular architectures.

Appointments and Affiliations

  • Assistant Professor of Chemistry
  • Member of the Duke Cancer Institute

Contact Information

  • Office Location: 1104 French Science Center, Durham, NC 27701
  • Office Phone: (919) 660-9438
  • Email Address: jennifer.roizen@duke.edu
  • Websites:

Education

  • Stanford University, 2013
  • Ph.D. California Institute of Technology, 2009
  • B.A. Williams College, 2003

Courses Taught

  • CHEM 202D: Organic Chemistry II
  • CHEM 202L: Organic Chemistry II
  • CHEM 393: Research Independent Study
  • CHEM 394: Research Independent Study
  • CHEM 493: Research Independent Study
  • CHEM 494: Research Independent Study
  • CHEM 532: Organic Reactions
  • CHEM 995: Graduate Training Internship

In the News

Representative Publications

  • Simons, RT; Scott, GE; Kanegusuku, AG; Roizen, JL, Photochemically Mediated Nickel-Catalyzed Synthesis of N-(Hetero)aryl Sulfamides., The Journal of Organic Chemistry, vol 85 no. 10 (2020), pp. 6380-6391 [10.1021/acs.joc.0c00139] [abs].
  • Short, MA; Blackburn, JM; Roizen, JL, Modifying Positional Selectivity in C-H Functionalization Reactions with Nitrogen-Centered Radicals: Generalizable Approaches to 1,6-Hydrogen-Atom Transfer Processes, Synlett, vol 31 no. 2 (2020), pp. 102-116 [10.1055/s-0039-1691501;ArtID:st-2019-p0583-sp] [abs].
  • Short, MA; Blackburn, JM; Roizen, JL, Modifying Positional Selectivity in C-H Functionalization Reactions with Nitrogen-Centered Radicals: Generalizable Approaches to 1,6-Hydrogen-Atom Transfer Processes., Synlett, vol 31 no. 2 (2020), pp. 102-116 [10.1055/s-0039-1691501] [abs].